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Showing posts with the label Methyl Iodide

Application of α-olefin SulfonateApplication of α-olefin Sulfonate

AOS (α-olefin sulfonate sodium salt) has very good comprehensive properties. It has mature technology, reliable quality and good detergency. Especially in hard water, it also shows the characteristic that the pollution power is basically not reduced. AOS has good biodegradability, and has been mass-produced and used in Japan, South Korea, India, and the United States. In China, it is being developed in fields such as oil field additives, starch processing aids, acrylate emulsion polymerization, mercerizing of cotton, wool washing, textile and paper wetting agents. It is expected that in the near future, α-olefin sulfonate will become a new generation of main synthetic detergent raw materials, and is widely used in household and industrial detergents. AOS is as gentle as AES, while LAS and AS are much more irritating than AOS. Therefore, AOS has a wide range of uses in personal care products. AOS is extremely stable under acidic conditions, and the skin of normal people is weakly aci...

Difference Between Sulfate And Sulfonate In Shampoo

Methyl iodide  has been highlighted as a potential genotoxic impurity (PGI). A sensitive HS-GC method with ECD was developed and validated for the determination of methyl iodide impurity in Tedizolid phosphate, an active pharmaceutical ingredient. HS-GC method on DB-624,column 60m × 0.53mm, film thickness 3μm, with electron capture detector (ECD) was used. The proposed method was specific, linear, accurate, rugged and precise. The calibration curves showed good linearity over the concentration range of 0.78 μg/g to 11.7 μg/g and the correlation coefficient was 0.997. Method had very low limit of detection (LOD) and limits of quantification (LOQ) are 0.23 μg/g and 0.78 μg/g, respectively, with respect to test concentration. Accuracy was observed within the range 96.0% to 103.2%. This method is a further extended good quality control tool for low level quantitation of methyl iodide impurity in another API, alogliptin benzoate. Methyl iodide is such a special electrophile, howeve...

Methyl Iodide Residual

Methyl iodide  has been highlighted as a potential genotoxic impurity (PGI). A sensitive HS-GC method with ECD was developed and validated for the determination of methyl iodide impurity in Tedizolid phosphate, an active pharmaceutical ingredient. HS-GC method on DB-624,column 60m × 0.53mm, film thickness 3μm, with electron capture detector (ECD) was used. The proposed method was specific, linear, accurate, rugged and precise. The calibration curves showed good linearity over the concentration range of 0.78 μg/g to 11.7 μg/g and the correlation coefficient was 0.997. Method had very low limit of detection (LOD) and limits of quantification (LOQ) are 0.23 μg/g and 0.78 μg/g, respectively, with respect to test concentration. Accuracy was observed within the range 96.0% to 103.2%. This method is a further extended good quality control tool for low level quantitation of methyl iodide impurity in another API, alogliptin benzoate. Methyl iodide is such a special electrophile, howeve...

Methyl Iodide Used in Pharmaceuticals

Iodomethane (Methyl iodide) is a colorless liquid. It can be prepared by reacting dimethyl sulfate with concentrated KI. In terms of chemical structure, it is related to methane by replacement of one hydrogen atom by an atom of iodine. It is naturally emitted by riceplantations in small amounts. It is also produced in vast quantities estimated to be greater than 214,000 tons annually by algae and kelp in the world's temperate oceans, and in lesser amounts on land by terrestrial fungi and bacteria. Iodomethane, more commonly called methyl iodide (MeI) is a volatile organic compound used in many chemical reactions. It is an excellent methylating agent that is used in pharmaceutical synthesis   as well as many organic syntheses. It is a vital catalyst for acetic acid manufacture and is an EPA registered soil fumigant. Approved pesticides, used to control insect, plant parasitic nematodes, soil borne pathogenes and weed seeds etc. Application: It is used in organic synthesis...

Anionic Surfactant

Anionic surfactant has a longest history, highest output and most various types. It is classified according to the structures of their hydrophilic groups: sulfonates and sulfates, which are the main types of anionic surfactants. The various functions of surfactants are mainly manifested in changing the properties of the liquid surface, the liquid-liquid interface and the liquid-solid interface. Sodium Laureth(2) Sulfate (AES/SLES) Chemical Formula: C12H26Na2O5S CAS No.: 68585-34-2 Dangerous Grade: Non-dangerous Sodium Alpha Olefin Sulfonate (AOS-35) Chemical Formula: R-CH=CH-(CH2)n-SO3Na CAS No.: 68439-57-6 Dangerous Grade: Non-dangerous C12-14 Linear Alkyl Benzene Sulfonate(LAS) Chemical Formula:C18H30O3S CAS No.:27176-87-0 Dangerous Grade: 8 Common anionic surfactant: Sulfate, sulfonate, and phosphate esters Anionic surfactants contain anionic functional groups at their head, such as sulfate,sulfonate, phosphate, and carboxylates. Prominent alky...

Cocamidopropyl Betaine In Skin Care

Coconut oil aminopropyl betaine(CAPB)can be extracted from coconut oil and dimethylaminopropylamine. CAPB is a surfactant. It can be added to personal care products or used in bath products such as shampoo and soap for washing hands. It's also an organic compound. And you can see from its name that the main part of its molecule, the lauric acid group, comes from coconut oil. CAPB is a medium-strength surfactant that can also be used in cosmetics and has an emulsifying and thickening effect. It can also be used as an antistatic agent in hair toners that do not irritate the skin or mucous membranes. It is also added to personal hygiene products as a preservative. Lipophilic, lipophilic and hydrophilic properties are chemical properties of surfactants, so surfactants can remove dirt and oil from the skin. Surfactants can reduce the surface tension of water, making it easier to wet, thus removing oil and dirt from the skin. So it's also a detergent Some surfactants are ver...